Scientific Program

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TOWARD PREVENTION AND EARLY INTERVENTION OF MAJOR MENTAL AND SUBSTANCE ABUSE DISORDERS

Major mental disorders impose a great burden on society. Preventing these disorders would provide immense benefit in terms of both money and human suffering. The 2005 meeting will address a number of key issues for making progress in preventing major mental disorders, ranging from the level of the DNA molecule to the level of governmental policy. Presentations will address how prevention efforts should be informed by an understanding of etiology and knowledge of indicators of vulnerability. Approaches to prevention at the level of public policy will be considered through presentations by representatives of the National Institutes of Health. Examples from areas of psychopathology that have already been the focus of considerable attention, such schizophrenia, Alzheimer's disease, substance abuse, antisocial personality disorder and PTSD, will be used to exemplify approaches to prevention.

Thursday, March 3, 2005
8:30 -- 9:15	Registration

9:15 -- 9:30	Welcome and Introduction
	Ming T. Tsuang, MD, PhD, UCSD/Harvard University

9:30 -- 9:45	Presentation Of Robins-Guze Award to Karestan Koenen, PhD, Harvard University

*SESSION 1*	*What Do We Know About the Etiology of Mental and Substance Abuse Disorders?*
	Chair: Charles F. Zorumski, MD, Washington University in St. Louis

9:45 -- 10:15	Finding Genetic Causes of Mental Disorders: Are There Lessons From Genomic Studies of Other Complex Traits?
	Mary-Claire King, PhD, University of Washington School of Medicine

10:15 -- 10:25	Discussion

10:25 -- 10:55	Environmental Determinants of Psychosis
	Robin M. Murray, DSc, FRCPsych, Institute of Psychiatry and Maudsley Hospital

10:55 -- 11:05	Discussion

11:05 -- 11:25	Coffee Break

11:25 -- 11:55	Psychosocial Factors in the Etiology of Psychiatric Disorders
	Jane M. Murphy, PhD, Harvard University

11:55 -- 12:05	Discussion

12:05 -- 12:15	Discussant and General Discussion

12:15 -- 12:25	Presentation of Hoch Award to Jane M. Murphy, PhD, Harvard University

12:25 -- 2:00	LUNCH

*SESSION 2*	*Vulnerability to Major Mental and Substance Abuse Disorders*
	Chair: Stephen L. Buka, ScD, Harvard University

2:00 -- 2:30	The Psychobiological Responses to Stress: A Prescription for Resilience
	Dennis Charney, MD, Mount Sinai School of Medicine

2:30 -- 2:40	Discussion

2:40 -- 3:10	Cognitive Vulnerability to Depression: Implications for Prevention
	Lauren B. Alloy, PhD, Temple University

3:10 -- 3:20	Discussion

3:20 -- 3:40	Coffee Break

3:40 -- 4:10	Vulnerability to Alcohol and Drug Use Disorders
	Deborah S. Hasin, PhD, Columbia University

4:10 -- 4:20	Discussion

4:20 -- 4:40	Discussant and General Discussion

5:30 -- 7:30	Poster reception

Friday, March 4, 2005
SESSION 3	Prevention: Lessons From Schizophrenia
	Chair: Larry Seidman, PhD, Harvard University

9:00 -- 9:30	Implications of Prodromal Studies for Prevention of Schizophrenia
	Barbara A. Cornblatt, PhD, MBA, Albert Einstein College of Medicine

9:30 -- 9:40	Discussion

9:40 -- 10:10	Adolescent Neurodevelopment: Critical Periods for Preventive Intervention
	Elaine Walker, PhD, Emory University

10:10 -- 10:20	Discussion

10:20 -- 10:40	Coffee Break

10:40 -- 10:50	Presentation of Joseph Zubin Award to: Nikki Erlenmeyer-Kimling, PhD, Columbia University

10:50 -- 11:20	Presidential Address: Toward the Prevention of Schizophrenia: Early Detection and Intervention
	Ming T. Tsuang, MD, PhD, UCSD/Harvard University

11:20 -- 11:30	Discussion

11:30 -- 11:50	Discussant and General Discussion

11:50 -- 12:20	APPA Business Meeting (Members Only)

12:20 -- 2:30	LUNCH

SESSION 4	NIH Perspectives on Prevention
	Chair: Lewis L. Judd, MD, University of California, San Diego

2:30 -- 3:00	Prospects for Prevention of Mental Illness
	Richard K. Nakamura, PhD, National Institute of Mental Health

3:00 -- 3:10	Discussion

3:10 -- 3:40	Addiction: The Neurobiology of Behavior Gone Awry
	Nora Volkow, MD, PhD, National Institute on Drug Abuse

3:40 -- 3:50	Discussion

3:50 -- 4:10	Coffee Break

4:10 -- 4:40	Alcoholism: A Developmental Perspective
	Ting-Kai Li, MD, National Institute on Alcohol Abuse and Alcoholism

4:40 -- 4:50	Discussion

4:50 -- 5:10	Discussant and General Discussion

Saturday, March 5, 2005
SESSION 5	Challenges for the Near Future
	Chair: Michael J. Lyons, PhD, Boston University

9:00 -- 9:30	Prevention of Alzheimer's Disease: Principles and Prospects
	John C.S. Breitner, MD, MPH, VA Puget Sound Health Care System

9:30 -- 9:40	Discussion

9:40 -- 10:10	Five Facts About Preventing Drug Dependence
	James C. Anthony, PhD, Michigan State University

10:10 -- 10:20	Discussion

10:20 -- 10:40	Coffee Break

10:40 -- 11:10	Prevention of Antisocial Behavior Disorder with a First-Grade Intervention
	C. Hendricks Brown, PhD, University of South Florida

11:10 -- 11:20	Discussion

11:20 -- 11:50	Secondary Pharmacological Prevention of PTSD
	Roger K. Pitman, MD, Harvard University

11:50 -- 12:00	Discussion

12:00 -- 12:20	Discussant and General Discussion

	Adjourn

This page was prepared by Gary Heiman, Ph.D. of Columbia University.

Revised September 13,2004